MPR1 — Magnaporthe oryzae 70-15

Summary

MoMPR1 (MPR1) from Magnaporthe oryzae 70-15 on chromosome 2 encodes an HPt domain-containing protein with histidine phosphotransfer kinase activity, acting as a histidine kinase binding and phosphorus-transferring enzyme. This gene is associated with osmolarity sensing via a two-component system, histidyl-aspartyl phosphorelay, negative regulation of mitotic entry, photomorphogenesis, regulation of cellular response to oxidative stress, glycerol metabolism, host invasion, biofilm formation, sporulation, morphogenesis, and stress response. Localised to the cytoplasm, cytosol, and nucleus, MoMPR1 is linked to blast disease in rice (Oryza sativa). Phenotypic associations include delayed cell cycle progression in M and S phases, abnormal chromosome segregation and spindle morphology, decreased hyperosmotic stress resistance, altered vegetative growth, and changes in chemical resistance and competitive fitness.