ABCA — Magnaporthe oryzae 70-15

Summary

MGG_07375 (MoABCA) on chromosome 3 of Magnaporthe oryzae 70-15 encodes an ABC transporter of the PDR/CDR subfamily, possessing ATP hydrolase and ATP-binding activities. The protein is associated with the plasma membrane and vacuolar membrane. It is associated with appressorium formation, response to toxic substances, xenobiotic detoxification via transmembrane export, hypersensitivity, cell death, DNA repair, protein dephosphorylation, and zearalenone biosynthetic processes. Associations also include abnormal small molecule transport, increased sporulation rate, decreased cell death rate, altered vacuolar distribution and transport, delayed exit from G0, increased fermentative growth, premature endocytosis, abnormal replicative and chronological lifespan, decreased sulfur utilization, and abnormal pseudohyphal growth. Studies of related genes in other species connect the family to traits such as plant height, root length, drought tolerance, and oxidative stress response, as well as reduced virulence.