MIH1 — Magnaporthe oryzae 70-15

Summary

MGG_07734 (MoMIH1) in Magnaporthe oryzae 70-15 encodes an M-phase inducer phosphatase with protein tyrosine phosphatase activity (EC 3.1.3.48), belonging to the MPI_Phosphatase and rhodanese-like domain families. The gene is associated with the positive regulation of the G2/M transition of the meiotic cell cycle, mitotic entry, and response to mitotic G2 DNA damage checkpoint signaling. It has been linked to pigmentation, asexual reproduction, appressorium formation, hyphal growth, morphogenesis, cell division, and chitin anabolism. The encoded protein localizes to the cytoplasm, cytosol, and nucleus. MoMIH1 is also linked to barley and rice blast disease. Studies of related genes in other species connect the family to traits such as root width, cell membrane stability, leaf shape, and protein content.