CP1 — Magnaporthe oryzae 70-15

Summary

MoCP1 (MGG_07861) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a serine carboxypeptidase, belonging to the peptidase S10 and alpha/beta hydrolase families. The gene is associated with proteolysis, chromatin silencing, and fHC assembly. Its product localises to the fungal-type vacuole, extracellular space, plasmalemma, and side of membrane. MoCP1 is linked to numerous cellular processes including autophagy, mitophagy, pexophagy, ribophagy, endocytosis, cytokinesis, protein secretion, nuclear fusion during mating, and entry into stationary phase. Associations with cell death, necrotic cell death, prion inheritance, aneuploidy, replicative lifespan, and acquired thermotolerance have also been observed. The gene is connected to several related carboxypeptidases including CPY1, KEX1, and PRC2.