CKI1 — Magnaporthe oryzae 70-15

Summary

MGG_08097 (MoCKI1) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a serine/threonine protein kinase with ATP and magnesium binding activity, classified as EC 2.7.11.1. The gene is associated with appressorium formation, hyphal growth, and interaction with the host, as well as regulation of filamentous growth, cell wall organization, endocytosis, and autophagy. It is linked to signal transduction, cellular responses to stress and xenobiotic stimuli, vacuolar protein sorting, and downregulation of bipolar cell polarity and protein localisation to the cell tip. The encoded protein localises to the cytoplasm, nucleus, cell periphery, plasmalemma, cell tip, division site, vacuolar lumen, fungal-type vacuole and its membrane, and extracellular vesicles. Associations with biofilm formation, cell cycle progression, vacuolar morphology, osmotic stress resistance, and intracellular transport have also been noted.