GAS1 — Magnaporthe oryzae 70-15

Summary

MGG_08370 (MoGAS1) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a glucanosyltransferase with 1,3-beta-glucanosyltransferase activity, belonging to the glycoside hydrolase superfamily and containing an X8 domain. The gene is associated with appressorium formation and maturation, host invasion, adhesion of symbiont to host, and development of symbiont in host. It is linked to fungal-type cell wall assembly and 1,3-beta-glucan metabolism, as well as cellular responses to pH, calcium ions, and the MAPK cascade. Associations include single-species biofilm formation, cell-substrate adhesion, division septum assembly, and innate immunity. The product localizes to the cell septum edging, primary cell septum, cellular bud membrane and scar, external side of the plasma membrane, lipid rafts, and sites of polarized growth. The gene is associated with blast disease in barley and rice.