GLS2 — Magnaporthe oryzae 70-15

Summary

MGG_08623 (GLS2, also known as MoGLS2, GH31-2, MoGH31-2, MoROT2, or ROT2) on chromosome 1 of Magnaporthe oryzae 70-15 encodes a glycoside hydrolase family 31 protein with glucan 1,3-alpha-glucosidase, alpha-glucosidase, and glucoamylase activities, and is a component of the glucosidase II complex in the endoplasmic reticulum. The gene is associated with appressorium formation and maturation, conidia formation, hyphal growth, sexual reproduction, cell wall organization, autophagy, detoxification, and biofilm formation. It is linked to carbohydrate, oligosaccharide, maltose, and polysaccharide breakdown, as well as N-glycan processing and fungal-type cell wall beta-glucan biosynthesis. Associations with blast disease in rice and barley have been noted. Studies of related genes in other species connect the family to cell cycle progression, nuclear fusion, protein secretion, and stress resistance.