RHD — Magnaporthe oryzae 70-15

Summary

MGG_08256 (MoRHD, also known as MoPRX1) encodes a mitochondrial peroxiredoxin PRX1, a thioredoxin-dependent peroxidase with protein-disulfide reductase activity and MAP kinase scaffold activity. In Magnaporthe oryzae, this gene is associated with the oxidative stress response, including cellular detoxification of hydrogen peroxide, metabolic burst, and cell redox homeostasis. It is linked to innate immunity, interaction with the host, and filamentous growth in response to chemical stimuli and starvation. The protein localizes to mitochondria, cytoplasm, nucleus, and the hyphal cell wall. MoRHD has been connected to blast disease in rice (Oryza sativa). Studies of related peroxiredoxin family members in other species link the family to oxidative stress response, though this is not yet established for MoRHD itself.