COR1 — Magnaporthe oryzae 70-15

Summary

MoCOR1 (MGG_08132) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a Cornichon family protein. The gene is associated with signaling receptor binding, appressorium formation, intracellular protein transport, and ER-to-Golgi vesicle transport, and localises to the ER, Golgi membrane, and COPII-coated vesicles. Phenotypic associations include absent sporulation efficiency, decreased lifespan, increased cell death, abnormal cytokinesis and meiosis, decreased colony size, increased mutation frequency, and abnormal spore wall formation. The gene is also linked to blast disease in rice and barley. Studies of related genes in other species connect the family to ER-derived vesicle cargo reception and, more distantly, to salt tolerance and potassium concentration traits.