PMC1 — Magnaporthe oryzae 70-15

Summary

MoPMC1 (MGG_07971) in Magnaporthe oryzae 70-15 encodes a P-type ATPase of the IIB subfamily, with molecular functions including potassium:proton transporter activity, calcium transporter activity, and ATP hydrolase activity. The gene is associated with conidium germination, ion membrane transport (potassium, sodium, calcium, manganese), cell pH regulation, and the response to unfolded protein. Its product localises to the plasma membrane, vacuolar membrane, Golgi membrane, and endoplasmic reticulum. Phenotype associations link MoPMC1 to abnormal Golgi distribution, absent spore germination, decreased necrotic cell death, increased ionic stress resistance, and altered vacuolar and endocytic transport. The gene is also connected to blast disease in barley and wheat. Related genes in other species link it to calcium sensitivity.