HIS3 — Magnaporthe oryzae 70-15

Summary

MGG_07528 (HIS3, also known as PTH3, MoHIS3, HIS5 or MoHIS5) on chromosome 3 of Magnaporthe oryzae 70-15 encodes an imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19). The gene is associated with histidine anabolism, pigmentation, asexual reproduction, appressorium formation, morphogenesis, signal transduction and phosphoglyceride metabolism. It is linked to blast disease in rice (Oryza sativa). Phenotypic associations include abnormal vegetative growth, colony appearance, cell shape, plasma membrane, endoplasmic reticulum and nucleolar morphology, increased cell death and filamentous growth, decreased invasive growth, ionic stress resistance, UV resistance, acid pH resistance, endocytosis and carbon source utilisation, as well as altered RNA accumulation and metal resistance.

Annotations

Chromosome
3
Related genes
HIS3, ECM16, LEU2, FRT2, DBP5, ERG3, URA3, RPB3
GO terms
Pigmentation, Asexual Reproduction, Imidazoleglycerol-phosphate Dehydratase Activity, Signal Transduction, histidine anabolism, morphogenesis, Appressorium Formation, phosphoglyceride metabolism
Publications
28768829, 33524398, 28585565, 19659576, 28869701, 12684846, 25182531, 11779853
Traits
RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, RNA ACCUMULATION: INCREASED, INVASIVE GROWTH: INCREASED, RNA LOCALIZATION: ABNORMAL