ATG17 — Magnaporthe oryzae 70-15

Summary

MGG_07667 (ATG17, MoATG17) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a protein with an ATG17-like domain and protein kinase activator activity, along with bridging binding capability. The gene is associated with autophagy, including mitophagy, pexophagy, and autophagy of the mitochondrion, as well as regulation of autophagy, glycogenolysis, protein phosphorylation, protein transport, the cell cycle, and S phase. Its product localises to the phagophore assembly site (PAS) and PAS membrane. The gene has been connected to blast disease in rice (Oryza sativa). Related genes in other species link it to the ULK complex.

Annotations

Chromosome
3
Related genes
ATG17
GO terms
Cell Cycle, S Phase, glycogenolysis, ULK complex, Protein Transport, PMN, binding, bridging, Autophagosome Assembly
Publications
PMID:20237561, PMID:19146970, PMID:28894236, PMID:32281734, PMID:37191531, PMID:38195499, PMID:40931865
Traits
increased virulence (hypervirulence), reduced virulence, loss of pathogenicity