PYR4 — Magnaporthe oryzae 70-15

Summary

MoPYR4 (PYR4) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a PaxB-like protein with lyase and isomerase activities. The gene is associated with UMP anabolism, terpenoid anabolism, and autophagy, as well as with appressorium formation, spore germination, and hyphal growth. It is linked to membrane localisation and to the oxidative stress response. Studies of related genes in other species connect the PaxB-like family to terpenoid biosynthesis and isomerisation reactions, though these functions are not yet established for MoPYR4 itself.