OGM2 — Magnaporthe oryzae 70-15

Summary

MGG_07190 (OGM2, also known as MoOGM2, PMT2, PMT3, PMT6) in Magnaporthe oryzae 70-15 on chromosome 2 encodes a dolichyl-phosphate-mannose–protein mannosyltransferase with protein O-mannosyltransferase activity (EC 2.4.1.109). The gene is associated with protein O-linked glycosylation, fungal-type cell wall organization, morphogenesis, filamentous growth, cell-substrate adhesion, interaction with host, and responses to neutral pH, starvation, and xenobiotic stimuli. It is linked to blast disease in rice (Oryza sativa) and barley (Hordeum vulgare). The product localizes to the ER membrane, nuclear membrane, endomembrane system, and plasmalemma. Related genes in other species are associated with loss of pathogenicity and mannose content.