DBP2 — Magnaporthe oryzae 70-15

Summary

MGG_07033 (DBP2, also known as DED1) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a DEAD-box RNA helicase with translation initiation factor activity, RNA helicase activity, mRNA and ATP binding, and ATP hydrolase activity. The protein localises to the cytoplasm, nucleus and spliceosome complex. It is associated with cytoplasmic translational initiation, negative regulation of that process in response to stress, RNA-dependent gene silencing, digestion, sexual reproduction and mating. Phenotype associations link the gene to abnormal mitotic recombination, absent sporulation efficiency, increased thermotolerance and gamma ray resistance, delayed vegetative growth and cell cycle progression, increased fermentative growth, and altered carbon source utilisation. Studies of related genes in other species connect it to oxidative stress response.