NAP1 — Magnaporthe oryzae 70-15

Summary

MoNAP1 (MGG_06924) in Magnaporthe oryzae 70-15 encodes a nucleosome assembly protein with H2A-H2B histone carrier activity, histone binding, chromatin binding, cyclin binding, and enzyme activator activity. It is associated with nucleosome assembly and disassembly, co-transcriptional chromatin reassembly, chromatin-mediated maintenance of transcription, and positive regulation of transcription elongation by RNA polymerase II. The gene is linked to appressorium formation, melanin anabolism, sporulation, hyphal growth, cell cycle modulation, and protein localization to the cell division site after cytokinesis. It localizes to the nucleus, cytoplasm, chromatin, hyphal septin ring, and bud neck. Associations with cell cycle progression, cytokinesis, mating efficiency, filamentous growth, adhesion, and nuclear transport have been reported. Studies of related genes in other species link the NAP1 family to cell cycle control and chromatin dynamics.