MPP — Magnaporthe oryzae 70-15

Summary

MoMPP (MGG_05258) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a protein with Pept_M16 and metalloenzyme LuxS/M16 domains, and is associated with metalloendopeptidase activity, signal peptidase activity, endopeptidase activator activity, structural molecule activity, and metal binding. The gene is associated with mitochondrial protein processing, mitochondrial electron transport (ubiquinol to cytochrome c), cellular respiration, proton transmembrane transport, defense response, invasive growth, and hyphal growth, and localizes to the mitochondrial inner membrane, mitochondrial lumen, complex III, and the mitochondrial processing peptidase complex. Phenotypic associations include decreased oxidative stress resistance, increased heat sensitivity, decreased competitive fitness, inviability, increased mutation frequency, abnormal chromosome/plasmid maintenance, increased chemical compound excretion, and altered chemical resistance. Studies of related genes in other species link the MPP family to invasive growth.