VAM7 — Magnaporthe oryzae 70-15

Summary

MGG_05428 (MoVAM7) on chromosome 1 of Magnaporthe oryzae 70-15 encodes a protein with a T-SNARE domain and a PX domain, and is annotated with SNARE and SNARE binding molecular functions as well as phosphoinositide binding. The gene is associated with vacuole fusion, vesicle fusion, Golgi to vacuole transport, macroautophagy, autophagic cell death, ferroptosis, appressorium formation and appressorium-mediated host invasion, defense response, actin cytoskeleton organization, and sexual reproduction. It is linked to the fungal-type vacuole membrane, late endosome, and SNARE complex. Associations with blast disease in rice and with turgor pressure have been noted. Related genes in other species connect the family to vacuolar morphogenesis and endocytosis.