ABC2 — Magnaporthe oryzae 70-15

Summary

MoABC2 (MGG_05595) on chromosome 1 of Magnaporthe oryzae 70-15 encodes a spermidine/putrescine import ATP-binding protein and an ABC-type oligopeptide transporter with ATP-coupled transmembrane transporter activity and ATP hydrolase activity. The gene is associated with host invasion, invasive growth, morphogenesis, cell wall biogenesis, autophagy, secondary metabolism, signal transduction, and siRNA-mediated post-transcriptional gene silencing. It is linked to mitochondrial inner membrane, endomembrane system, and plasmalemma localisation. Phenotypic associations include altered cell cycle progression, increased entry into G0 stationary phase, decreased hyperosmotic and hypo-osmotic stress resistance, abnormal vacuolar morphology and distribution, increased pexophagy, decreased endocytosis, abnormal colony color, and altered protein/peptide accumulation rates. The gene is also associated with oligopeptide export from mitochondria, retrotransposition, and regulation of cell growth.