TY-1 — Magnaporthe oryzae 70-15

Summary

MGG_05199 (MoTY-1, also known as MoSTE50) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a protein containing a Ras-association (RA) domain, a SAM/pointed superfamily domain, and a ubiquitin-like domain superfamily. The gene is associated with appressorium formation, the MAPK cascade, invasive growth, morphogenesis, and signal transduction, as indicated by ontology annotations. MoTY-1 has been linked to blast disease in rice (Oryza sativa). Studies of related genes in other species, such as the MAPKKK cascade protein kinase regulator Ste50, connect the family to similar signaling and pathogenicity processes in species including Verticillium dahliae and Fusarium oxysporum.