CAT2 — Magnaporthe oryzae 70-15

Summary

MGG_04337 (CAT2, KATG1) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a catalase-peroxidase (EC 1.11.1.21) with haem peroxidase and metal-binding domains. The gene product exhibits catalase and peroxidase activities, binds heme, and is localised to the cytosol. CAT2 is associated with the catabolism of hydrogen peroxide, the cellular response to hydrogen peroxide, and appressorium formation. It is also linked to genetic transfer processes. Studies of related genes in other fungi connect the family to oxidative stress response, and sequence similarity links CAT2 to homologues in Verticillium dahliae and Fusarium oxysporum pathovars.