OGM4 — Magnaporthe oryzae 70-15

Summary

MGG_04427 (symbol MoOGM4, also known as MoPMT4) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a protein O-mannosyltransferase (EC 2.4.1.109) with protein O-mannosyltransferase activity, belonging to the PMT_4TMC and ArnT-like_N domain families. The gene is associated with protein O-linked glycosylation, fungal-type cell wall organization, filamentous growth, cell-substrate adhesion, interaction with host, and responses to starvation, neutral pH, and xenobiotic stimuli. It is linked to blast disease in both barley (Hordeum vulgare) and rice (Oryza sativa). The encoded protein localizes to the ER membrane, nuclear membrane, endomembrane system, and plasmalemma. Studies of related genes in other species link the family to loss of pathogenicity and altered mannose content.