TIF — Magnaporthe oryzae 70-15

Summary

MGG_04400 (TIF1) in Magnaporthe oryzae 70-15 encodes a DEAD-box RNA helicase with translation initiation factor activity, ATP hydrolase and RNA binding functions, and is located in the cytoplasm and stress granules. The gene is associated with defense response, innate immunity, immune response, cytoplasmic translational initiation, homologous recombination, hyphal growth, and signal transduction. It has been linked to abnormal chemical compound excretion and accumulation, increased vacuolar transport, decreased RNA localization, absent peroxisomal transport and morphology, absent apoptosis and mitotic recombination, absent spindle morphology, delayed protein/peptide distribution, absent prion inheritance, decreased M-phase cell cycle progression, premature anaphase and G1/S transition, delayed exit from G0, absent anaerobic growth, absent nuclear export, abnormal fermentative metabolism, and abnormal vacuolar distribution. Studies of related genes in other species link the family to protein content.