SMI1 — Magnaporthe oryzae 70-15

Summary

MGG_03970 (MoSMI1, also known as MoCOT-2) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a glucan synthesis regulatory protein belonging to the Knr4/Smi1 family. The product possesses protein-binding bridging and DNA-binding molecular functions. MoSMI1 is associated with fungal-type cell wall beta-glucan anabolism, mitotic division septum assembly, mitotic cell cycle modulation, regulation of fungal-type cell wall biogenesis, nucleosome assembly, cell wall organization, and DNA-dependent transcription. It localizes to the intracellular vesicle, incipient cellular bud site, mating projection tip, cellular bud neck, cell division site, and nucleus. The gene is linked to barley (Hordeum vulgare) and rice blast disease. Related genes in other species, such as Verticillium dahliae and Fusarium oxysporum pathovars, are linked to the Knr4/Smi1 family.