CP1 — Magnaporthe oryzae 70-15

Summary

MoCP1 (MGG_03995) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a serine carboxypeptidase, belonging to the peptidase S10 and alpha/beta hydrolase families, with serine carboxypeptidase activity. The gene is associated with proteolysis, chromatin silencing, and fHC assembly. Its product localises to the fungal-type vacuole, extracellular space, plasmalemma, and side of membrane. Phenotypic associations link MoCP1 to altered cell death, autophagy, mitophagy, pexophagy, ribophagy, endocytosis, cytokinesis, protein secretion, nuclear fusion during mating, nuclear position, Golgi morphology, aneuploidy, prion inheritance, thermotolerance, replicative lifespan, and entry into stationary phase. Related genes in other species connect the family to apoplastic effector function and the enzyme classifications EC 3.4.16.5 and 3.4.16.6.