TRX2 — Magnaporthe oryzae 70-15

Summary

MGG_04236 (TRX2) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a thioredoxin family protein with a thioredoxin domain and conserved active-site motif, possessing protein-disulfide reductase activity and antioxidant activity. The gene is associated with cell redox homeostasis, cellular detoxification of hydrogen peroxide, and the hydrogen peroxide catabolic process, as well as with toxic metabolite repair, fatty acid oxidation, the TCA cycle, oxidative phosphorylation, and the glycerophosphate shuttle. TRX2 is associated with appressorium formation, melanin anabolism, and invasive growth, and is linked to protein desuccinylation. The encoded product localises to the cytoplasm, cytosol, nucleus, and vacuole. Studies of related genes in other species link the family to similar redox and pathogenic processes.