RGA1 — Magnaporthe oryzae 70-15

Summary

MGG_04186 (MoRGA1) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a Rho GTPase-activating protein (RhoGAP) with a Znf_LIM domain, annotated with GAP activity, small GTPase binding, phosphoinositide binding, and lipid binding. The gene is associated with downregulation of Rho protein signal transduction, regulation of actin cable assembly, positive regulation of establishment of cell polarity regulating cell shape, positive regulation of establishment of bipolar cell polarity, mitotic division septum assembly, regulation of cell wall organization or biogenesis, appressorium formation, defense response, immune response, and negative regulation of cell integrity MAPK cascade. It is linked to phenotypes including abnormal bipolar budding, decreased septum formation, altered cell cycle progression, increased mating efficiency, abnormal filamentous growth, and decreased necrotic cell death. Related genes in other species include BUD14.