CHS1 — Magnaporthe oryzae 70-15

Summary

MGG_04145 (MoCHS1, CHS1) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a chitin synthase with chitin synthase activity (EC 2.4.1.16), belonging to the chitin synthase fungal and N-terminal domain families. The gene is associated with cell wall organization, chitin anabolism, cytokinesis, septum positioning, mitotic actomyosin contractile ring contraction, nuclear division, mitotic exit, hyphal growth, conidia formation, appressorium formation, invasive growth, and host invasion. It localizes to the plasma membrane, cell periphery, cellular bud neck, and cross wall. Associations include abnormal septum formation, absent septum formation, abnormal chitin deposition, decreased adhesion, decreased flocculation, abnormal bipolar and axial budding patterns, absent budding, abnormal bud neck morphology, decreased cell fusion, decreased cell death, increased respiratory and fermentative metabolism, increased survival in stationary phase, abnormal entry into G0, decreased G2 phase duration, arrested late anaphase, delayed M phase, premature metaphase and telophase, abnormal shmoo formation, increased pheromone sensitivity, decreased chromosome segregation, and abnormal spore wall formation.