CDA — Magnaporthe oryzae 70-15

Summary

MGG_04172 (CDA) in Magnaporthe oryzae 70-15, located on chromosome 6, encodes a protein with a NodB domain and a glycosyl hydrolase/deacetylase domain, and has chitin deacetylase activity, hydrolase activity acting on carbon-nitrogen (but not peptide) bonds, chitin binding, zinc binding, and metal binding. This gene is associated with appressorium formation, immune evasion, chitin breakdown, polysaccharide breakdown, cell wall organization, carbohydrate metabolism, morphogenesis, and cell death. The encoded protein is localized extracellularly. CDA is linked to rice blast disease and to turgor pressure. Studies of related genes in other species connect the family to EC 3.5.1.104 and EC 3.5.1.41, as well as to peptidoglycan N-deacetylase and glycosyl hydrolase functions.