ACT — Magnaporthe oryzae 70-15

Summary

MoACT (MGG_03982) on chromosome 6 of Magnaporthe oryzae 70-15 encodes an actin family protein with an actin/actin-like conserved site and an ATPase nucleotide-binding domain and is a structural constituent of the cytoskeleton. It is associated with the actin cytoskeleton and localizes to hyphal tips, cell tips, and sites of polarized growth. The gene is associated with regulation of growth, pigmentation, appressorium formation, conidia formation, hyphal and invasive growth, endocytosis, and host invasion. Associations with traits include oxidative stress response. Phenotypic associations include abnormal sporulation efficiency, delayed cytokinesis and protein secretion, decreased cell cycle progression, and absent cell fusion and anaerobic growth. Studies of related genes in other species link the family to reduced virulence and infection.