PTC4 — Magnaporthe oryzae 70-15

Summary

MGG_03918 (MoPTC4) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a protein phosphatase 1K with MAPK phosphatase activity and protein serine/threonine phosphatase activity, belonging to the PP2C and PPM-type phosphatase families. The gene is associated with conidiophore development, hyphal growth, regulation of aerobic respiration, downregulation of MAPK cascades, cellular osmotic and oxidative stress responses, and positive regulation of non-autophagic vacuole fusion. It is linked to turgor pressure, increased hydrostatic pressure resistance, increased alkaline pH resistance, decreased cold sensitivity, increased entry into G0 stationary phase, absent filamentous growth, decreased colony size, decreased chitin deposition, abnormal mitochondrial distribution, and altered respiratory and fermentative metabolism. The encoded protein localises to the fungal-type vacuole membrane, mitochondria, cytoplasm, cytosol, and nucleus. Related genes in other species have been linked to phosphate content and acid sensitivity.