TPS1 — Magnaporthe oryzae 70-15

Summary

MGG_03860 (TPS1) in Magnaporthe oryzae 70-15 encodes a trehalose-6-phosphate synthase, an enzyme with trehalose synthase and trehalose-phosphatase activities (EC 2.4.1.15) that also exhibits transglucosylase and nucleotide-binding functions. This gene is associated with trehalose biosynthesis and catabolism, glucose and phosphate metabolism, the pentose-phosphate shunt, carbon catabolite repression, and cellular responses to desiccation, hydrogen peroxide, glucose, and stress. It is linked to appressorium formation, ascospore formation, filamentous growth in response to heat, and cell wall assembly. The protein localises to the cytosol, nucleus, and trehalose-6-phosphate synthase complex. Associations with turgor pressure and numerous phenotypes including altered thermotolerance, cell cycle progression, biofilm formation, spore germination, desiccation resistance, and hypoosmotic stress resistance have been recorded. Studies of related genes in other species link the family to sporogenesis, calcium sensitivity, and oxidative stress response.