ATP2 — Magnaporthe oryzae 70-15

Summary

MoATP2 (MGG_03185) on chromosome 4 of Magnaporthe oryzae 70-15 encodes the ATP synthase subunit beta, a component of the F1F0 ATPase complex. The product possesses proton-transporting ATP synthase activity, ATP binding and hydrolase activity, and ADP binding. It localises to the mitochondrial inner membrane, the vacuolar V1 domain, the plasmalemma, and the fungal-type vacuole membrane. The gene is associated with proton-motive-force-driven mitochondrial ATP synthesis, ATP metabolism, cellular chemical homeostasis, vacuolar acidification, autophagy, immune response, and appressorium formation. Phenotypic associations include altered oxidative phosphorylation, mitochondrial transport, cell cycle progression, spore germination, adhesion, mating efficiency, desiccation resistance, and colony colour. Studies of related genes in other species link the family to respiratory growth, cell cycle progression, and necrotic cell death.