ABC2 — Magnaporthe oryzae 70-15

Summary

MoABC2 (MGG_03406) encodes an iron-sulfur clusters transporter ATM1, a mitochondrial ABC transporter with ATP hydrolase activity and ATP-coupled transmembrane transporter activity. Localised to the mitochondrial inner membrane, it is associated with iron-sulfur cluster export and assembly, cellular iron ion homeostasis, host invasion, invasive growth, morphogenesis, cell wall biogenesis, autophagy, secondary metabolism, signal transduction, and siRNA-mediated post-transcriptional gene silencing. The gene is linked to numerous phenotypes including abnormal cell cycle progression, decreased endocytosis, altered vacuolar morphology, increased pexophagy, and changes in stress resistance and colony colour. Related genes in other species connect it to oxidative stress response and leaf morphology traits.