ALP2 — Magnaporthe oryzae 70-15

Summary

MGG_03670 (ALP2, also known as SPM1, MoISP6, or MoALP2) in Magnaporthe oryzae 70-15 on chromosome 4 encodes a serine-type endopeptidase (EC 3.4.21.-) belonging to the peptidase S8 subtilisin-related family. The gene is associated with proteolysis, protein catabolic processes in the vacuole, and amino acid breakdown. It is linked to appressorium formation, asexual sporulation, spore germination, invasive growth, host invasion, autophagy, pexophagy, cytokinesis, morphogenesis, and secondary metabolism. The encoded product is also associated with IgE binding and localizes to the vacuole and extracellular space. Related genes in other species link the family to virulence in pathogens such as Fusarium oxysporum and Verticillium dahliae. The gene has been associated with blast disease in rice and barley.