ORLA — Magnaporthe oryzae 70-15

Summary

MGG_03441 (MoORLA, also known as MoTPS2 or MoTPP1) on chromosome 4 of Magnaporthe oryzae 70-15 encodes a trehalose-phosphatase with trehalose synthase and transglucosylase activities, containing Glyco_trans_20 and HAD-like domains. The gene is associated with mycose biosynthesis and metabolism, cellular responses to desiccation, heat, and stress, as well as filamentous growth, ascospore formation, and cell wall assembly. It localises to the cytosol, nucleus, and trehalose-6-phosphate synthase complex. MoORLA is associated with increased acquired thermotolerance, freeze-thaw resistance, and starvation resistance, alongside abnormal mating response, absent spore germination, and altered cell cycle progression. Related genes in other species are linked to sporogenesis, oxidative stress response, and acid sensitivity.