SEC3 — Magnaporthe oryzae 70-15

Summary

MoSEC3 (MGG_03323) on chromosome 4 of Magnaporthe oryzae 70-15 encodes an exocyst complex component Sec3 PIP2-binding N-terminal domain-containing protein with a Sec3_C domain and a Sec3-PIP2_bind domain, with molecular function in phosphatidylinositol-4,5-bisphosphate binding. The gene is associated with exocytosis, Golgi-to-plasma membrane transport, and salicylic acid anabolism, and localises to the exocyst and plasma membrane. It is linked to abnormal filamentous growth, delayed sporulation, absent spore germination, decreased adhesion, altered cell cycle progression, delayed cytokinesis, abnormal Golgi and vesicle distribution, and decreased necrotic cell death. Related genes in other species connect the family to exocyst function, protein secretion, and cell polarity.