CHS7 — Magnaporthe oryzae 70-15

Summary

MoCHS7 (MGG_03122) on chromosome 4 of Magnaporthe oryzae 70-15 encodes a protein with unfolded protein binding activity (GO:0051082). The gene is associated with chitin anabolism, cell wall organization, appressorium formation, invasive growth, hyphal growth, morphogenesis, ER-to-Golgi transport, protein transport, and protein folding, and its product localizes to the ER membrane. Associations with traits and phenotypes include altered turgor pressure, decreased chitin deposition, abnormal cell wall morphology, increased hydrostatic pressure and osmotic stress resistance, altered mating and sporulation efficiency, decreased filamentous and pseudohyphal growth, increased viability and biofilm formation, and changes in mitotic recombination, silencing, and apoptosis. The gene is linked to related genes such as CHS6, CHS3, SMI1, GAS1, CLA4, and TOR1. Studies of related genes in other species connect the family to reduced virulence.