PMC1 — Magnaporthe oryzae 70-15

Summary

MoPMC1 (MGG_02487) on chromosome 1 of Magnaporthe oryzae 70-15 encodes a P-type ATPase of the IIB subfamily with potassium:proton transporter activity, K+-transporting ATPase activity, and additional annotations for sodium, manganese, and calcium transport. The gene is associated with conidium germination, ion membrane transport, cell pH regulation, and responses to unfolded protein. It localises to the plasma membrane, vacuolar membrane, Golgi membrane, lipid rafts, and extracellular vesicles. Phenotypic associations include abnormal Golgi distribution, absent spore germination, decreased necrotic cell death, increased ionic stress resistance, and altered vacuolar and endocytic transport. The gene is linked to rice blast disease. Related genes in other species connect it to calcium sensitivity and reduced virulence.