DBF2 — Magnaporthe oryzae 70-15

Summary

MoDBF2 (MGG_02757) on chromosome 7 of Magnaporthe oryzae 70-15 encodes a serine/threonine protein kinase with AGC-kinase and protein kinase domains, exhibiting protein serine/threonine kinase activity, ATP binding, and identical protein binding. The gene is associated with salicylic acid anabolism, systemic acquired resistance, and regulation of filamentous growth, biofilm formation, and protein secretion. It is linked to mitotic cytokinesis, actomyosin organization, nuclear migration, spindle elongation, and septum biogenesis, with localization to the spindle, actomyosin contractile ring, hyphal tip, and spindle pole body. Associations include blast disease in rice, cell cycle progression, chromosome segregation, bipolar budding, septum formation, and redox state. Studies of related genes in other species connect the family to the Sid2-Mob1 complex.