DBP2 — Magnaporthe oryzae 70-15

Summary

MGG_02806 (DBP2/SUB2) in Magnaporthe oryzae 70-15 encodes a DEAD-box RNA helicase with ATP hydrolase activity, RNA helicase activity, mRNA binding, identical protein binding, RNA binding, and ATP binding. It is associated with mRNA nuclear export, mRNA 3'-end processing, RNA splicing via the spliceosome, transcription elongation from RNA polymerase II promoter, telomeric silencing, TC-NER, digestion, sexual reproduction, mating, and mRNA transport. The product localizes to the TREX complex, spliceosome complex, and chromosome telomeric region. Phenotypic associations include abnormal mitotic recombination, decreased mating type switching, absent or abnormal sporulation efficiency, altered cell cycle progression (including G2/M and G1/S transitions), delayed vegetative and exponential growth, increased thermotolerance and gamma ray resistance, increased fermentative growth, and altered carbon source utilization. Related genes in other species link the family to oxidative stress response.