SSZ1 — Magnaporthe oryzae 70-15

Summary

MoSSZ1 (MGG_02842) on chromosome 7 of Magnaporthe oryzae 70-15 encodes an Hsp70-like protein with ATP hydrolase activity, peptide binding, protein translocase activity, and heat shock protein binding, and is annotated as a protein folding chaperone and transcriptional co-regulator. It is associated with protein folding and refolding, the ER unfolded protein response, ERAD pathway, SRP-dependent and posttranslational membrane targeting and translocation, regulation of ribosome biogenesis and translational fidelity, fungal-type cell wall beta-glucan anabolism, cellular response to heat and osmotic stress, and karyogamy. The gene is linked to rice blast disease and barley. Phenotypic associations include increased chemical compound accumulation, premature apoptosis, altered cell cycle progression, abnormal fermentative metabolism, increased adhesion, and decreased UV resistance.