SSK1 — Magnaporthe oryzae 70-15

Summary

MoSSK1 (MGG_02897) on chromosome 7 of Magnaporthe oryzae 70-15 encodes a response regulatory domain-containing protein with histidine kinase activity, phosphorelay sensor kinase activity, and ATP binding. The gene is associated with the regulation of filamentous growth, cellular responses to oxidative stress, heat, neutral pH, farnesol, and starvation, as well as osmolarity sensing via the two-component system, activation of the p38 cascade, glycerol metabolism, immune evasion, host invasion, and negative regulation of mitotic entry. MoSSK1 localises to the membrane, cytoplasm, cell division site, and the Mcs4 RR-MAPKKK complex. It is linked to blast disease in rice (Oryza sativa). Studies of related genes in other species connect the family to histidine kinase activity (EC 2.7.13.3), germination rate, oxidative stress response, and altered virulence.