ARG5 — Magnaporthe oryzae 70-15

Summary

MGG_02690 (MoARG5) on chromosome 7 of Magnaporthe oryzae 70-15 encodes an acetylglutamate kinase. The gene is associated with N-acetyl-gamma-glutamyl-phosphate reductase activity, acetylglutamate kinase activity, NADP+ binding, NAD binding, and ATP binding. It is linked to pigmentation, the urea cycle, sexual reproduction, regulation of DNA-templated transcription, arginine anabolism, hyphal growth, and protein synthesis. The encoded protein localises to the mitochondria and mitochondrial lumen. MoARG5 is associated with blast (rice) and Hordeum vulgare. Associations with numerous phenotypes include decreased filamentous and invasive growth, altered stress resistance, increased replicative and chronological lifespan, abnormal mitochondrial transport and genome maintenance, and decreased mitophagy and pexophagy.