PACC — Fusarium graminearum PH-1

Summary

FgPACC (FGRAMPH1_01G22981) on chromosome 4 of Fusarium graminearum PH-1 encodes a Znf_C2H2-type transcription factor of the pacC/RIM101 family. The product binds DNA and zinc, and is associated with cellular response to basic pH, homeostasis, spore germination, sporulation, cell growth, homologous recombination, mycotoxin anabolism, and positive regulation of transcription by RNA polymerase II. It localises to both the cytoplasm and nucleus. Studies of related genes in other species link the pacC/RIM101 family to pH response, sugar content, and altered virulence—including hypervirulence and reduced virulence—as well as to diseases such as fusarium ear blight and blast.