pac1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G17349 (symbol pac1) on chromosome 3 of Fusarium graminearum PH-1 encodes a protein with an RNase III domain, conferring dsRNA-specific RNase activity, RNA hairpin binding, and ribonuclease III activity. The product localises to the nucleoplasm and nucleolus. It is associated with RNA metabolism, including nuclear mRNA breakdown, rRNA processing, U2 and U4 snRNA 3'-end processing, box C/D snoRNA 5'-end processing, termination of RNA polymerase II transcription, and meiotic cell cycle. The gene is also linked to homeostasis. Related genes in other species encode ribonuclease III proteins.