XLNR — Fusarium graminearum PH-1

Summary

FgXLNR (FGRAMPH1_01G17629) on chromosome 3 of Fusarium graminearum PH-1 encodes a Zn2Cys6 DNA-binding transcription factor of the XlnR/Xlr1 family. The protein localises to the nucleus and has DNA-binding and RNA polymerase II-specific transcription factor activity. FgXLNR is associated with the positive regulation of xylan and cellulose breakdown, as well as broader processes including regulation of transcription by RNA polymerase II and positive regulation of macromolecule metabolic processes. Studies of related genes in other species link the family to vascular wilt and fusarium ear blight, though pathogenicity appears unaffected in some relatives.