ABC2 — Fusarium graminearum PH-1

Summary

FgABC2 (FGRAMPH1_01G10921) on chromosome 2 of Fusarium graminearum PH-1 encodes an ABC-type oligopeptide transporter with ATP hydrolase activity and ATP-coupled transmembrane transporter activity, belonging to the type 1 exporter family. The gene is associated with oligopeptide export from the mitochondrion, sterol anabolism, secretion, membrane transport, and homeostasis. Its product localises to the mitochondrial inner membrane, plasmalemma, and membrane. FgABC2 is associated with abnormal colony color, decreased hyperosmotic and hypo-osmotic stress resistance, absent oxidative stress resistance, altered cell cycle progression, increased pexophagy, decreased endocytosis rate, and abnormal vacuolar morphology. Studies of related genes in other species connect the family to leaf width and shape traits, as well as oxidative stress response.