ABCA — Fusarium graminearum PH-1

Summary

FgABCA (FGRAMPH1_01G11451) on chromosome 2 of Fusarium graminearum PH-1 encodes an ABC transporter of the PDR/CDR subfamily, possessing ATP hydrolase activity and ATP binding. This protein is associated with the plasma membrane and linked to extracellular transport, xenobiotic detoxification, response to toxic substances, and toxin anabolism. It has also been connected to seed germination, DNA repair, and hypersensitivity. Phenotypic associations include increased sporulation rate, decreased cell death, and abnormal vacuolar distribution, nutrient uptake, and pseudohyphal growth. Studies of related genes in other species link the family to reduced virulence and unaffected pathogenicity, as well as traits such as plant height, root length, and drought tolerance.