CAT2 — Fusarium graminearum PH-1

Summary

FgCAT2 (FGRAMPH1_01G11747) on chromosome 2 of Fusarium graminearum PH-1 encodes a catalase-peroxidase with catalase and peroxidase activities, heme binding, and metal binding. It belongs to the haem peroxidase superfamily. The gene is associated with hydrogen peroxide catabolism, the cellular response to hydrogen peroxide, and coenzyme A and acetyl-CoA transport, and its product localises to the cytosol. Studies of related genes in other species link the family to oxidative stress response and to virulence on wheat and maize, including head blight, stalk rot, ear rot, and seedling blight, though pathogenicity phenotypes vary.

Annotations

Chromosome
2
Related genes
cat2, CAT2
GO terms
Acetyl-CoA Transport, metal binding, Cytosol, Peroxidase Activity, Heme Binding, H2O2 catabolic process, Cellular Response To Hydrogen Peroxide, Catalase Activity
Publications
PMID:12761140, PMID:20237561, PMID:19000033, PMID:21971530, PMID:18498226, PMID:24558260, PMID:39069064, PMID:17086155
Traits
unaffected pathogenicity, reduced virulence, oxidative stress response